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Unravelling intestinal inflammation: from Celiac Disease genotype to autoimmunity.

Unravelling intestinal inflammation: from Celiac Disease genotype to autoimmunity. - CeD: From genotype to autoimmunity.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON44698
Enrollment
2500
Registered
2014-06-24
Start date
2015-02-26
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Celiac Disease Gluten-intolerance

Interventions

None listed

Sponsors

Genetica
Lead Sponsor

Eligibility

Age
2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults (patients and control subjects UMCG & Martini Ziekenhuis Groningen; controls Wilhelmina Ziekenhuis Assen): -Patients suffering from CeD diagnosed by the treating physician according to established clinical, serological and pathological definitions. - Patients suffering from IBS as diagnosed by the treating physician according to established clinical defined in the Rome II criteria. -Spouses and 1st line family members of CeD patients - >= 18- years old;Children (Patienten Wilhelmina Ziekenhuis Assen): -Patients suffering from CeD diagnosed by the treating physician according to established clinical, serological and pathological definitions. -

Exclusion criteria

Exclusion criteria: not applicable

Design outcomes

Primary

MeasureTime frame
The primary study parameters will be the data sets generated by the different 'omics' approaches and the results of the integration of these datasets.

Secondary

MeasureTime frame
These analyses will identify CeD biomarkers and the identification of these will provide novel insights into the etiopathology of CeD. This will help in the future with improving diagnostics and treatment, and hopefully the prevention of CeD.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)