Decubitus pressure sores Pressure ulcers
Conditions
Interventions
None listed
Sponsors
Technische Universiteit Eindhoven
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Group 1 * Adult * Have a sensory and motor complete lesion, ASIA A between L1 and C4 * Lesion acquired less than 1 year ago * Possible to collect a non-contaminated urine sample (e.g. naturally controlled urination, clean intermittent catheterisation, indwelling catheter with a sample port) * Signed informed consent ;Group 2+4 * Adult * Have a sensory and motor complete lesion, ASIA A between L1 and C4 * Lesion acquired over 1 year ago. * Possible to collect a non-contaminated urine sample (e.g. naturally controlled urination, clean intermittent catheterisation, indwelling catheter with a sample port) * Signed informed consent ;Group 3 * Adult * In good health * Signed informed consent
Exclusion criteria
Exclusion criteria: All groups * Mental disability that hinders the ability to understand and comply with the informed consent * Diagnosed skin disease * Oncological patients * If a subject is unable to obtain urine samples themselves and do not have assistance. * Fever (temperature > 38*C) will lead to temporary exclusion * Have had a pressure ulcers diagnosed in the past 6 months.;Extra exclusion criteria for group 1+2+3 * Active infections at the start of the study (determined by POCT CRP) will lead to temporary exclusion * If a subject in the home situation does not have the ability to store samples at minus 20*C.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The concentration of several biomarkers in urine. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine possible causes for changes in biomarker concentration not associated with a PU. | — |
Countries
Netherlands
Outcome results
None listed