Dihydropyrimidine dehydrogenase (DPD) deficiency and haematological abnormalities

Dihydropyrimidine dehydrogenase (DPD) deficiency and haematological abnormalities - DPD deficiency

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44558

Enrollment

Registered

2017-09-01

Start date

2017-12-18

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dihydropyrimidine dehydrogenase deficiency

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: - genetically and/or biochemically confirmed DPD deficiency - written permission to participate to the study by the participant and/or the parents/caregivers in case of children or incompetent adults

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
To establish whether or not DPD deficient patients suffer from an altered white blood cell homeostasis, in particular that of B or T lymphocytes.	—

Secondary

Measure	Time frame
To investigate the function of white blood cells from DPD deficient patients.	—

Countries

Netherlands

Outcome results