posttraumatic stress
Conditions
Interventions
None listed
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Between 18 and 45 years of age. • Predominant right-handedness. • Normal or corrected-to-normal vision • Normal uncorrected hearing • Body mass index between 18.5 and 30 • Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements
Exclusion criteria
Exclusion criteria: • Abnormal hearing or (uncorrected) vision. • Average use of more than 3 alcoholic beverages daily. • Average use of psychotropic medication or recreational drugs weekly or more. • Use of psychotropic medication, or of recreational drugs over a period of 72 hours prior to each test session, and use of alcohol within the last 24 hours before each measurement. • Regular use of corticosteroids. • Metal objects in or around the body (e.g., braces, pacemaker, metal fragments, insulin pump, and hearing devices). • Metal fragments in the body, in particular in the eye. • Using a medical plaster that cannot or may not be taken off. • History of neurological treatment or current neurological treatment. • History of endocrine treatment or current endocrine treatment. • History of head surgery. • Current parodontitis. • Claustrophobia. • Epilepsy. • Pregnancy. • Irregular sleep/wake rhythm (e.g., regular nightshifts or cross timeline travel). • Experience in law enforcement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psychophysiological recordings (electrodermal activity, electromyographic activity, breathing rate, heart rate, pupil diameter) Behavioral recordings (reaction times, decision making, memory performance) Brain function (f)MRI) Self-report questionnaires & and one clinical interview | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary cortisol, alpha-amylase and testosterone Hair hormones (cortisol, testosterone) Epigenetic and genetic profiles as assessed from saliva | — |
Countries
Netherlands
Outcome results
None listed