onderzoek bij gezonde vrijwilligers not applicable
Conditions
Interventions
transcranial magnetic stimulation: continuous theta-burst stimulation (three 50
Hz pulses every 200 ms for 40 seconds, 80% AMT) with a Magpro-X-100 magnetic
stimulator (MagVenture, Farum, Denmark)
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Between 18 and 35 years of age* Righthanded* Nonsmoking* Normal or corrected to normal vision* Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.
Exclusion criteria
Exclusion criteria: (1) Average use of more than 3 alcoholic beverages daily* (2) Use of psychotropic medication or recreational drugs* (3) Skin disease* (4) Pregnancy* (5) Serious head trauma or brain surgery* (6) Neurological or psychiatric disorders* (7) Large or ferromagnetic metal parts in the head (except for a dental wire)* (8) Implanted cardiac pacemaker or neurostimulator* (9) Participation in a NBS study in the past 28 days* (10) Previous participation in 10 or more NBS studies; (11) epilepsy or family history of epilepsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alpha-beta oscillations in the EEG as well as naming latencies and error rates in the language production task following real or sham cTBS | — |
Secondary
| Measure | Time frame |
|---|---|
| AMTs of the left and right primary motor cortex and resting-state EEG prior to cTBS | — |
Countries
Netherlands
Outcome results
None listed