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Glioma stem cell organoids: preclinical model of glioblastoma heterogeneity to explore resistance mechanisms to conventional treatment schedules.

Glioma stem cell organoids: preclinical model of glioblastoma heterogeneity to explore resistance mechanisms to conventional treatment schedules. - Patient-derived glioma stem cell organoids.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON44469
Enrollment
30
Registered
2017-09-08
Start date
2018-04-10
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glioma Primary brain tumor

Interventions

None listed

Sponsors

MAASTRO Lab
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • MRI imaging suggestive for glioblastoma • > 18 years of age

Exclusion criteria

Exclusion criteria: • Karnofsky index

Design outcomes

Primary

MeasureTime frame
Intra-and inter organoid genetic and epigenetic heterogeneity that is representative for GM

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)