Liver Fibrosis in a Home Parenteral Nutrition Cohort

Liver Fibrosis in a Home Parenteral Nutrition Cohort - Fibrosis in a HPN cohort

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44440

Enrollment

Registered

2017-09-01

Start date

2017-11-13

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinaal Falen (verschillende onderliggende oorzaken mogelijk bijvoorbeeld: Short Bowel, Passagestoornissen, Microvili inclusieziekte) Intestinal Failure Associated Liver Disease (IFALD) TPN associated liver disease

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: * Written informed consent from parent(s)/caregiver(s) and if applicable subject (when *12 years of age) * Must be enrolled in the HPN-programme of the ECH-AMC. * Must receive HPN for at least 3 months continuously.

Exclusion criteria

Exclusion criteria: * Age

Design outcomes

Primary

Measure	Time frame
Prevalence of fibrosis according to Transient Elastography (TE).	—

Secondary

Measure	Time frame
- Correlation between TE values and ELF test score and APRI. - Correlation between TE values and standard laboratory liver parameters such as AP, GGT, Bilirubin and transaminases. - Correlation between TE values and known risk factors for the development of IFALD.	—

Countries

Netherlands

Outcome results