Non-Invasively recorded high frequency oscillations as biomarkers in focal epilepsy

Non-Invasively recorded high frequency oscillations as biomarkers in focal epilepsy - MEG-EEG HFO Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44429

Enrollment

Registered

2015-03-18

Start date

2015-08-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

convulsion epileptic fit Epileptic seizure

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Patients have refractory focal epilepsy (not responding to treatment with anti-epileptic drugs) and are candidates for epilepsy surgery in the University Medical Center Utrecht with pre or intra operative corticography (measuring brains signals during surgery). - Adults and children over six - EEG and MEG compatible

Exclusion criteria

Exclusion criteria: -Patients who undergo epilepsy surgery outside the UMCU, or without pre or intra operative corticography -Patients with metal implants (not MEG compatible) -Patients under six and other patients unable to lie down or sit motionless for at least 15 minutes (not MEG compatible)

Design outcomes

Primary

Measure	Time frame
- The number of patients with HFOs with each technique (corticography, scalp EEG, MEG) - The number of HFOs per minute with each technique - The brain aeas showing HFOs with each technique	—

Secondary

Measure	Time frame
- The number of seizures before and after surgery - The results of cognitive tests before and after surgery	—

Countries

Netherlands

Outcome results