Simultaneous right heart cauterisation and echocardiography in patients with pulmonal arterial hypertension to validate the non-invasive deformation-area loop

Simultaneous right heart cauterisation and echocardiography in patients with pulmonal arterial hypertension to validate the non-invasive deformation-area loop - Pressure-volume loop vs. deformation-area loop

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44427

Enrollment

Registered

2017-10-10

Start date

2018-04-11

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

increased pressure in the pulmonal artery Pulmonary arterial hypertension

Interventions

deformation-area loop

echocardiography

pressure-volume loop

Pulmonal arterial hypertension

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Suspected pulmonary arterial hypertension Above 18 years Voluntary participation

Exclusion criteria

Exclusion criteria: Cardiovascular diseases, other than pulmonary arterial hypertension Diabetes Mellitus

Design outcomes

Primary

Measure	Time frame
The primary study parameters are the correlation between the different measures for contractility and compliance from the strain-area loop and the pressure-volume loop. • The relation between the end-systolic pressure-volume relationship (ESPVR) the slope of the systolic part of the strain-area loop (Sslope). • The relation between the end-diastolic pressure-volume relationship (EDPVR) the slope of the diastolic part of the strain-area loop during passive filling.	—

Measure

Time frame

The primary study parameters are the correlation between the different measures for contractility and compliance from the strain-area loop and the pressure-volume loop. • The relation between the end-systolic pressure-volume relationship (ESPVR) the slope of the systolic part of the strain-area loop (Sslope). • The relation between the end-diastolic pressure-volume relationship (EDPVR) the slope of the diastolic part of the strain-area loop during passive filling.

—

Secondary

Measure	Time frame
• dP/dT of the pressure-volume loop • de maximale eind-systolische strain	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)