Diabetic cardiovascular Autonomic Neuropathy in patients undergoing major abdominal and cardiothoracic Surgery

Diabetic cardiovascular Autonomic Neuropathy in patients undergoing major abdominal and cardiothoracic Surgery - DANS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44422

Enrollment

Registered

2014-08-18

Start date

2014-10-08

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes neuropathy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: diabetes mellitus planned for cardio-thoracic surgery or major gastro-intestinal surgery

Exclusion criteria

Exclusion criteria: Parkinsons disease Pure autonomic failure Multiple system atrophy with autonomic failure (Shy-Drager syndrome) Addison*s disease and hypopituitarism Pheochromocytoma Peripheral autonomic neuropathy (e.g., amyloid neuropathy, idiopathic autonomic neuropathy) Known cardiomyopathy Extreme left ventricle hypertrophy Ejection fraction

Design outcomes

Primary

Measure	Time frame
- The incidence of DAF in this population - The relation between the stage of autonomic failure and hemodynamic changes	—

Secondary

Measure	Time frame
- Ejection fraction postoperative compared to preoperatively in patients undergoing cardiac surgery. - Mean glucose during surgery, glucose increase during surgery, hyperglycaemia (>10 mmol/l) during surgery - Plasma creatinine difference before and day 0, 1 and 2 after surgery - Length of ICU and/or in-hospital stay - Length of inotropic dependent hours after surgery - In-hospital mortality	—

Countries

Netherlands

Outcome results