To assess the anabolic response following protein ingestion muscle growth muscle protein synthesis
Conditions
Interventions
Assess the muscle protein synthetic response after ingestion of a protein
beverage.
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-35 y 2) BMI 18.5-27.5 kg/m2 3) Healthy, recreationally active, young adults
Exclusion criteria
Exclusion criteria: 1) Allergies to milk protein 2) Lactose intolerance 3) PKU disease 4) Smoking 5) Diagnosed diabetes 6) Diagnosed metabolic or intestinal disorders 7) A history of neuromuscular problems 8) Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications) 9) Participation in structured resistance exercise program 10) Pregnant 11) Hormone replacement therapy 12) Third generation oral contraceptives 13) Strict vegetarian
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| muscle bound L-[ring-2H5]-phenylalanine, L-[1-13C]-phenylalanine, and L-[1-13C]-leucine enrichments (in MPE) plasma L-[ring-2H5]-phenylalanine and L-[1-13C]-leucine enrichments (in MPE) | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma amino acid, glucose en insulin concentrations, "whole-body" metabolism | — |
Countries
Netherlands
Outcome results
None listed