Typing of endometrial lymphocytes of (unexplained) recurrent miscarriage patients

Typing of endometrial lymphocytes of (unexplained) recurrent miscarriage patients - TERM-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44412

Enrollment

Registered

2018-01-30

Start date

2017-07-18

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unexplained recurrent miscarriage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient group: Normotensive women aged 18-45 years with a history of 3 or more consecutive, idiopathic pregnancy losses before

Exclusion criteria

Exclusion criteria: - Use of immunosuppressive drugs, biological or antidepressants - Use of birth control (exception condom) - HIV positivity - Auto-immune diseases - Diabetes mellitus - Smoking - Participants who are not capable of signing the informed consent - Patients will be excluded if there is a known cause for the miscarriages like e.g. the presence of anti-thyroid, anti-phospholipid and anti-nuclear autoantibodies, endocrine dysfunction, uterine malformation, hemostatic disorder, and abnormal karyotype.

Design outcomes

Primary

Measure	Time frame
Differences in phenotype and function of immunological cells present in menstrual blood of patients and controls.	—

Countries

Netherlands

Outcome results