Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy individuals: - Perceived healthy - Age >= 18 years - Written informed consent PD Patients: - able to walk (Hoehn & Yahr scale: Stage 2-3) - trouble initiating gait (as reported in the medical file) - PD diagnosis according to the UK Parkinson*s Disease Society Brain Bank criteria (A.J. Hughes, 1992) - Age
Exclusion criteria
Exclusion criteria: All participants - (other) neurological or motor disorder (for patients: other than PD) - Use of medication influencing movement (for patients: other than for PD)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gait velocity over the initial two meters and full six meters of walking after starting as determined using (i) a stopwatch and distance markers or (ii) IMU signals, comparing gait initiation with and without forward arm extension. | — |
Secondary
| Measure | Time frame |
|---|---|
| left and right step length as derived from IMU signals, compared between gait initiation with and without arm extension. Correlation between the primary and secondary outcome parameters and the MDS-UPDRS (Part III) motor score and item gait (3.10), in particular. Correlation between the primary study parameters and subjective assessment of changes in gait performance. | — |
Countries
The Netherlands