The state of the (sentinel) lymph node and tumour microenvironment in patients with cancer of the cervix.

The state of the (sentinel) lymph node and tumour microenvironment in patients with cancer of the cervix. - Microenvironment lymph nodes and tumour cervical cancer

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44376

Enrollment

100

Registered

2018-02-16

Start date

2018-06-11

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer cervix carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years at start of the study; Primary carcinoma of the cervix; Operation at the NKI-AVL or AMC/VUmc; Signed informed consent.

Exclusion criteria

Exclusion criteria: Patients

Design outcomes

Primary

Measure	Time frame
To analyse the microenvironment of (sentinel) lymph node(s) and primary tumour (i.e. antigen presenting cells and other immune cells) and other immune factors produced by the tumour cells in patients with cervical cancer.	—

Secondary

Measure	Time frame
- to assess the difference of the microenvironment of tumour-negative and metastatic lymph nodes - to assess the difference of the microenvironment of sentinel lymph nodes and non-sentinel lymph nodes - to analyse the difference in the (sentinel) lymph nodes compared to the primary tumour - to assess the effect of the cervical tumour on the systemic immunity	—

Countries

Netherlands

Outcome results