Revealing individual neural underpinnings of anxiety in healthy subjects

Revealing individual neural underpinnings of anxiety in healthy subjects - neural phenotype of anxiety

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44325

Enrollment

250

Registered

2017-10-30

Start date

2017-11-24

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety

Interventions

anxiety

fMRI

neuronal networks

proof-of-concept study

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: healthy volunteers (18-50 years) fMRI compartibility

Exclusion criteria

Exclusion criteria: History of or current neurological or psychiatric treatment History of or current brain surgery or epilepsy Pregnancy Metal parts in the upper body, implants, medical devices or medicinal plasters Claustrophobia

Design outcomes

Primary

Measure	Time frame
In the fMR session three paradigms will be tested to determine the neural phenotype: - prefrontal regulation task - salience processing task - face processing task	—

Secondary

Measure	Time frame
questionnaires: - HADS (Hospitality Anxiety and Depression Scale, Zigmond & Snaith, 1983) - FEEL-E (Emotional Adjustment Questionnaire for Adults, Grob & Horowitz, 2014) - BDI (Becks Depression Inventory, Beck, Steer, & Brown, 1996) Biological markers for stress: - heart rate - skin conductance	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)