Acute and delayed effects of marathon running on cardiac and skeletal muscle damage

Acute and delayed effects of marathon running on cardiac and skeletal muscle damage - Cardiac and skeletal muscle damage following marathon running

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44267

Enrollment

Registered

2017-07-21

Start date

2017-09-18

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise-induced cardiomyopathy / Cardiac Fatigue

Interventions

cardiac damage

exercise

skeletal muscle

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Marathon runners, >45 years of age, healthy

Exclusion criteria

Exclusion criteria: known cardiovascular diseases, unable to undergo MRI-scan

Design outcomes

Primary

Measure	Time frame
The primary outcome is the MRI characterization of cardiac and skeletal muscle damage (i.e. edema / diffuse fibrosis / late gadolinium enhancement / etc.).	—

Secondary

Measure	Time frame
Secondary outcomes include concentrations of cardiac biomarkers (troponin I, BNP), ECG characteristics and exercise intensity (heart rate) during marathon running.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)