Glaucoma POAG
Conditions
Interventions
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - To have participated in one of the relevant past cross-sectional studies conducted in our lab. - Signed informed consent.
Exclusion criteria
Exclusion criteria: For all subjects: - Development of ophthalmological or neurological disorders which affect the retina, optic nerve or the brain since the last study - Refusal to be informed in the event of discovering a brain abnormality in the brain scans - Use of recreational drugs or medications which may influence neurodegenerative progression - General contraindications of MRI (including MR-incompatible implants and tattoos, and claustrophobia) Only for controls: - Visual acuity lower than 0.8
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For T1-weighted MRI scan: GM volume, WM volume, cortical thickness, cortical surface area, and mean curvature. For Diffusion-weighted MRI scan: Fractional anisotropy (FA) and mean diffusivity (MD). | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in primary parameters between follow-ups. Time interval between follow-ups. | — |
Countries
The Netherlands
Outcome results
None listed