Intraoperative assessment of microcirculation with Laparoscopic Laser Speckle Analysis (lapLASCA) in patients elected for colorectal surgery for prediction of anastomotic leakage in colorectal anastomoses.

Intraoperative assessment of microcirculation with Laparoscopic Laser Speckle Analysis (lapLASCA) in patients elected for colorectal surgery for prediction of anastomotic leakage in colorectal anastomoses. - LapLASCA research

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44223

Enrollment

100

Registered

2014-03-18

Start date

2015-11-04

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anastomotic leakage suture leakage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - elected surgery - right (extended) hemicolectomie -transverse colectomy - sigmoid colectomy - (low) anterior rectal resection - Hartmann reversal surgery -Laparoscopic procedure

Exclusion criteria

Exclusion criteria: * Elected for subtotal colectomy * Elected for abdominoperineal resection * Elected for temporary colostomy procedures * Septic patients (anastomotic leakage) * Emergency surgeries

Design outcomes

Primary

Measure	Time frame
1. The mean speckle contrast, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have developed anastomotic leakage 2. The mean microcirculatory flow, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have developed anastomotic leakage 3. The mean speckle contrast, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have not developed anastomotic leakage 4. The mean microcirculatory flow, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have not developed anastomotic leakage All 4 primary parameters are measured during the folowing critical moments during elected colorectal surgery: a. Before vascular ligation (baseline): b. At a reference, coecum or sigmoid (baseline) c. After vascular ligation d. After colon division at the proximal and distal stump e. On the anastomosis	—

Measure

Time frame

1. The mean speckle contrast, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have developed anastomotic leakage 2. The mean microcirculatory flow, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have developed anastomotic leakage 3. The mean speckle contrast, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have not developed anastomotic leakage 4. The mean microcirculatory flow, intraoperative, of the colon or rectum in patients, with 532nm and 660nm light, who have not developed anastomotic leakage All 4 primary parameters are measured during the folowing critical moments during elected colorectal surgery: a. Before vascular ligation (baseline): b. At a reference, coecum or sigmoid (baseline) c. After vascular ligation d. After colon division at the proximal and distal stump e. On the anastomosis

—

Secondary

Measure	Time frame
All other riskfactors related to anastomotic literature found in literature	—

Countries

Netherlands

Outcome results