Detection of Mast cells in Systemic Mastocytosis

Detection of Mast cells in Systemic Mastocytosis - DOMIS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44206

Enrollment

Registered

2014-11-17

Start date

2014-08-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mast cell disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Older than 18 years Diagnosed with systemic mastocytosis according to WHO criteria Informed written consent

Exclusion criteria

Exclusion criteria: Younger than 18 years No informed consent

Design outcomes

Primary

Measure	Time frame
To study the reliable identification of mast cells in peripheral blood of patients with systemic mastocytosis and investigate if numbers and/or phenotype (expression of aberrant markers) differ from healthy controls.	—

Secondary

Measure	Time frame
To study numbers and phenotype of other leukocyte subsets (with an emphasis on IgE+ B cells) in peripheral blood of patients with SM compared to healthy controls.	—

Countries

Netherlands

Outcome results