biologische klok, alertheid, slaperigheid, metabolisme biological clock
Conditions
Interventions
2 3-day FD protocols separated by a 3-week rehabilitation period
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Gezonde mannelijk proefpersonen Leeftijd: 20-30 Schriftelijke ondertekening van het toestemmingsformulier
Exclusion criteria
Exclusion criteria: Colour blindness Sleeping problems Usage of (recreational) drugs Smoking Moderate to high levels of caffeine intake Diabetic disease Shift work scheduled 3 months prior to participation Travel over 2 or more time zones prior to participation PSQI>5 Epworth Sleepiness Scale >10 Glasses Use of photosensitizing medication or sleep medication Use of melatonin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are melatonin rhythms (saliva samples) and core body temperature (CBT) to test whether a short FD protocol can be used as an alternative to a multiple-week FD protocol in disentangling homeostatic and circadian components affecting alertness, sleep, heart rate, metabolism and body temperature. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are subjective sleepiness, subjective and objective sleep quality, metabolic rate, heart rate, core body temperature and skin temperature, to investigate whether light can affect alertness (and whether this effect depends on the circadian clock). | — |
Countries
Netherlands
Outcome results
None listed