Advanced imaging in HIPEC for peritoneal carcinomatosis of colorectal origin; a feasibility study

Advanced imaging in HIPEC for peritoneal carcinomatosis of colorectal origin; a feasibility study - Advanced imaging techniques for detection of peritoneal carcinomatosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON44157

Enrollment

Registered

2016-03-07

Start date

2016-05-12

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peritoneal Carcinomatosis Peritoneal Metastases

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Oral and written informed consent -Age 18 years and older -Elective cytoreductive surgery followed by HIPEC -Regular preoperative work-up -Laparoscopic or open approach

Exclusion criteria

Exclusion criteria: -ASA score higher than 3 -Patients who have had prior major open abdominal surgery -Contraindicattions for ICG, 5-ALA or ICB -Medication that interacts with ICG, 5-ALA or ICB -Chronic kidney failure (eGFR 2 times normal value)

Design outcomes

Secondary

Measure	Time frame
Operating time Blood loss Peritoneal carcinomatosis index (PCI) score (Serious) adverse events Patient characteristics Tumour characteristics	—

Primary

Measure	Time frame
To evaluate the sensitivity of Narrow Band Imaging, Three-dimensional imaging, Near-infrared Indocyanin Green Imaging, 5-ALA fluorescent imaging and Indigo Carmine Blue Spray Dye Chromoendoscopy in the detection of malignant lesions. To evaluate if more malignant lesions are found with NBI, 3D, NIR-ICG, 5-ALA and SDCE, compared to conventional white light laparoscopy.	—

Countries

Netherlands

Outcome results