Verstandelijke beperking Depression sadness
Conditions
Interventions
Each individual participant from the two light therapy groups (the group with
the 10,000 lux light box and the group with the 100-499 lux light box) will
receive bright light therapy (in the morning
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Minimal age of 18 years. - Intellectual disability (IQ*70). - Informed consent. - A depression or observable symptoms of depression.
Exclusion criteria
Exclusion criteria: - Bipolar disorder type 1 or type 2 (because the risk of the occurrence of a manic episode). - When the diagnosis 'dementia' is made **by a physician or behavioral scientist. - If there is suicidal behavior or currently suicidal expressions. - When an individual has or has had a hypomanic episode, manic episode or psychotic episode. - When there is or has been a prepartum and/or postpartum depression. - If the participant has a delirium. - When the lens of the eye is missing (aphakia) .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure in this study is the severity of depressive symptoms as measured with the Depressive mood subscale of the Anxiety, Depression and Mood Scale (ADESS). The depressive symptoms of participants in both light therapy groups are compared with the depressive symptoms of participants who don't get light therapy (care as usual). | — |
Secondary
| Measure | Time frame |
|---|---|
| Besides the primary study parameter we will also investigate whether there is a significantly larger effect when light therapy is given with lamp model 1 compared to lamp model 2. And we examine whether any observed effect of light therapy still exists after a period of 4 weeks (follow-up measurement). For these two secondary study parameters we will also use the Depressive mood subscale of the Anxiety, Depression and Mood Scale (ADESS). Any existing diagnosis of major depressive disorder according to the criteria of the DSM IV is made prior to the intervention. The researcher will (after extensive training) decline a diagnostic interview for all participants. We use the Dutch translation of the PAS-ADD (Psychiatric Assessment Schedule for Adults with Developmental Disability, Clinical Interview). Besides depressive symptoms we will also investigate the effect of lighttherapy on the circadian rhythm (Actiwatch and DLMO) and stress level (cortisol level), expectations of the caregiver (and, if possible, of the participant) over the effect of light therapy on depressive symptoms of the participant and the number of days the intervention is deployed (compliance). Personal and environmental characteristics will be retrieved from the participants' medical and psychological files and we investigate the number of life events of the participant in the past year. | — |
Countries
Netherlands
Outcome results
None listed