obesitas perioperative surgical conditions
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: ASA 1-3, 18 years or older; BMI > 34 kg/m2; ability to give informed consent; elective bariatric surgery.
Exclusion criteria
Exclusion criteria: Known or suspected neuromuscular disorders impairing neuromuscular function; allergies to muscle relaxants, anesthetics or narcotics; A (family) history of malignant hyperthermia; Women who are or may be pregnant or are currently breast feeding; Renal insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical conditions, with as main research question *Does a deep surgical block indeed improve surgical conditions in case of laparoscopic surgery in morbidly obese patients for bariatric surgery?* The surgical condition will be determined from a surgical rating condition scale, the Leiden Surgical rating Scale. This is a 5-point ordinal scale ranging from 1 = poor condition to 5 = optimal surgical conditions. The surgeon will score the condition at 15 min intervals. At the time of scoring also the intra-abdominal pressure will be monitored. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end-points include: (1) The hemodynamics during surgery with the main research question *Does a deep neuromuscular block coincide with improved hemodynamics during surgery and less postoperative pain?* (2) Cardiorespiratory conditions in the post-anesthesia care unit, with the main research question *What is the effect of reversal with Sugammadex of a deep surgical muscle block on postoperative breathing activity as measured by respiratory rate and saturation* (3) Pain and sedation in the post-anesthesia care unit, with the main research question *Does a deep block coincide with less pain compared to a moderate block in the recovery period?* and (4) The Postoperative Quality of Recovery Scale (PQRS), with the main question *Irrespective of depth of the neuromuscular block during surgery, is the quality of recovery similar in patients that were reversed with sugammadex*. | — |
Countries
Netherlands
Outcome results
None listed