cardiac decompensation chronic heart failure
Conditions
Interventions
In the final review group of 6 patients, the cardiologist will use the 3D
venogram and fused MRI and CT images during CRT implantation, to optimize the
LV lead position.
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: An indication Cardiac Resynchronization Therapy according to the current international evidence based guidelines for CRT (the 2013 European Society of Cardiology Guidelines for cardiac pacing and cardiac resynchronization therapy): -Chronic heart failure; -New York Heart Association functional class II, III, IV (ambulatory); -QRS duration *120ms; -Optimal pharmacological therapy; -Left ventricular ejection fraction *35%;;And specifically for phase 1 of the study: -Documented history of myocardial infarction, coronary artery disease, or delayed enhancement on a prior MRI.
Exclusion criteria
Exclusion criteria: -Contraindications for implantation of a CRT device; -Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility - Quality of MRI; - Quality of CT; - Quality of treatment file (CARTBox3); - Quality of 3D venogram; - Fusion feasibility; - Fluoroscopy time; - Contrast dose CT; - Radiation dose CT; - Radiation dose of CRT implantation; - Complications during CRT implantation; - Implantation duration.; - Patient repositioning; - Number of additional 3D images. | — |
Secondary
| Measure | Time frame |
|---|---|
| LV lead parameters (recorded of each possible position). -Lead/electrode position in RAO 30° en LAO 40° view; -Lead/electrode position in 3D view; -Distance of lead/electrode to infarct location; -Distance of lead/electrode to phrenic nerve position; -Distance of lead/electrode to latest activated segment; -Pacing and n. phrenicus threshold; -Type of LV lead; -QLVsense (of each electrode); | — |
Countries
Netherlands
Outcome results
None listed