The use of perioperative antibiotic prophylaxis in the treatment of acute cholecystitis, a randomized, multicenter, non-inferiority trial

The use of perioperative antibiotic prophylaxis in the treatment of acute cholecystitis, a randomized, multicenter, non-inferiority trial - PEANUTS 2

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON43999

Enrollment

454

Registered

2015-11-24

Start date

2016-03-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis inflamed gallbladder

Interventions

Omitting antibiotic prophylaxis

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Acute calculous cholecystitis, defined as mild or moderate according to Tokyo Guidelines * Cholecystectomy * Written informed consent

Exclusion criteria

Exclusion criteria: *

Design outcomes

Primary

Measure	Time frame
The primary outcome measure is the development of postoperative infections (surgical site and distant infections) within 30 days after surgery.	—

Secondary

Measure	Time frame
Secondary endpoints are the individual postoperative infections, other postoperative complications, duration of hospital stay and total costs.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)