Complex appendicitis Simple appendicitis
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: 3.1 Population (base) All children 0-17 presenting at the ER department in one of the three hospitals with the suspicion of an acute appendicitis are eligible for inclusion.;3.2 Inclusion criteria (in the simple or complex appendicitis group) All children 0-17 presenting at the ER department in one of the three hospitals with the suspicion of an acute appendicitis are eligible for inclusion.;3.3 Control group Children presenting at the ER with abdominal pain with the suspicion of acute appendicitis, although non-infectional cause or no cause was found however.
Exclusion criteria
Exclusion criteria: Age older than 17 years old Appendicular infiltrate Appendectomy a froid Appendix Sana Malignancy of the appendix Non-operative management Abdominal pain caused by other infectious disease such as lymphadenitis mesenteric, pneumonia etcetera.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Type of appendicitis, gender, age, symptoms at time of presentation, duration of abdominal pain, fever, heart rate, laboratory results at the time of diagnosis, findings on radiological imaging. Per operative findings and conclusion. Immunology: levels of cytokines, kind of leucocytes in peripheral blood samples. Histopathology: number and kind of immune cells in the appendix. Cellular staining by flowcytometry Bacteriology: Microbiome | — |
Secondary
| Measure | Time frame |
|---|---|
| nvt | — |
Countries
Netherlands
Outcome results
None listed