Appearance of endometrial tissue outside the womb Endometriosis
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -Oral and written informed consent -Age 18 years and older -Premenopausal women -Elective laparoscopic treatment of endometriosis lesions by CO 2 laser/ bipolar diathermy or surgical excision. -Presence of endometriosis (ASRM III-V) confirmed by previous laparoscopy or likely to be present based on TVUS or MRI, including uni- or bilateral ovarian endometrioma. -Regular preoperative work-up
Exclusion criteria
Exclusion criteria: -Women who are legally or mentally incapable or unable to give informed consent -Age younger than 18 years -ASA (American Society of Anaesthesiologists) score higher than 3 -Woman who have had major open abdominal surgery -Pregnancy -Malignancy -Iodine allergy -Hypersensitivity reaction to prior indocyanine green injection -Hyperthyoidism or autonomous thyroid adenoma -Chronic kidney failure (eGFR two times the max normal value)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the sensitivity and specificity of Narrow Band Imaging, near-infrared imaging with ICG and 3D-laparoscopy compared to conventional white light laparoscopic imaging. To evaluate if more endometriosis lesions are found with 3D, NBI and ICG compared to conventional white light laparoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| -Descriptive analysis of the by endometriosis affected ovaries and intestines -Use of hormonal therapy -Use of pain medication -Operating time -Blood loss -(Serious) adverse events | — |
Countries
Netherlands
Outcome results
None listed