The diagnostic accuracy of the Dutch DYMUS, a 10-item questionnaire to assess dysphagia in multiple sclerosis.

The diagnostic accuracy of the Dutch DYMUS, a 10-item questionnaire to assess dysphagia in multiple sclerosis. - Validation of DYMUS-NL; a questionnaire for swallowing disorders in MS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43967

Enrollment

Registered

2016-07-28

Start date

2016-09-19

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

difficulty swallowing Swallowing disorders

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: (1) at least 18 years of age (2) a confirmed diagnosis of MS (3) mentally competent to give informed consent and (4) able to follow instructions and to respond autonomously to questionnaires.

Exclusion criteria

Exclusion criteria: (1) individuals with obstruction in nasal passage (FEES will not be possible) (2) individuals with other neurological disorders (3) individuals with significant cognitive deficits who cannot follow instructions during FEES (4) individuals who are medically not stable enough to be able to participate in FEES (e.g. pneumonia or fever). and (5) individuals who are mentally incompetent to give informed consent.

Design outcomes

Primary

Measure	Time frame
Diagnostic accuracy: to determine the sensitivity and specificity (ROC curves and Positive Predictive Value/Negative Predictive Value (PPV/NPV)) of the DYMUS with FEES.	—

Secondary

Measure	Time frame
- the reproducibility of the DYMUS (test/re-test, smallest real difference (SRD)). - the diagnostic accuracy of the DYMUS compared with different swallowing tests (i.e. the Volume-Viscosity Swallow Test (V-VST) and the yes/no question (Do you have difficulty swallowing?). - the influence of the presence of cognitive impairment (based on the Symbol Digit Modalities Test (SDMT)) on the DYMUS results.	—

Measure

Time frame

- the reproducibility of the DYMUS (test/re-test, smallest real difference (SRD)). - the diagnostic accuracy of the DYMUS compared with different swallowing tests (i.e. the Volume-Viscosity Swallow Test (V-VST) and the yes/no question (*Do you have difficulty swallowing?*). - the influence of the presence of cognitive impairment (based on the Symbol Digit Modalities Test (SDMT)) on the DYMUS results.

—

Countries

Netherlands

Outcome results