The effect of acute exercise and fitness level on the aging brain, an investigation with fMRI

The effect of acute exercise and fitness level on the aging brain, an investigation with fMRI - How does exercise affect the brain?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43951

Enrollment

100

Registered

2016-04-11

Start date

2016-05-02

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aging cognitive functioning

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Normal (or corrected to normal) vision, healthy, fMRI compatible, no (history of) neurological or psychiatric disorders, fluent in Dutch. Age range: 18-30 or 50-65.

Exclusion criteria

Exclusion criteria: Smoking. Health issues that could influence the ability to exercise, MR incompatable (posibility of any incompatible metal objects inside the body), alcohol/drug abuse, answering 'yes' to one or more questions on the r-PARQ. MR incompatible, based on the fMRI questionnaire. This includes (but is not limited to) claustrophobia, presence of MR incompatible implants, such as pacemakers or insulin pumps, (suspicion of) pregnancy, tattoo(s) that contain red pigment.

Design outcomes

Primary

Measure	Time frame
Main study parameters are functional MRI measurements during two N-back tasks (during the exercise and control session), the effects of fitness level on AB task performance and pupil dilation signal, CBF measurements during two resting states (pre and post exercise).	—

Secondary

Measure	Time frame
The secundary parameter of the proposed study is the BOLD signal of resting state networks, measured during the resting state scans before and after acute exercise.	—

Countries

Netherlands

Outcome results