Coronary artery disease myocardial ischemia
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Stable angina pectoris • Nuclear MPI within the last 60 days • Scheduled for ICA • Patients must provide consent in writing after proper education and discussion with the treating physician and/or research physician • 50 years or older
Exclusion criteria
Exclusion criteria: • Cardiac rhythm other than sinus • Second or third degree atrioventricular block • Prolonged QT-time • Sick-sinus syndrome • Asthma or chronic obstructive pulmonary disease • Contraindications for iodine contrast • Thyroid gland disorders • Renal insufficiency (eGFR 65 bpm and contraindications for beta-blocker • Severe arterial hypertension (>220/120 mmHg) • Severe arterial hypotension (35) • Severe physical deterioration due to concomitant illness • Language barrier • Acute coronary syndrome • Pregnancy • Claustrophobia • Using of persantin, theophylline, digoxin or verapamil, if temporarily stopping (48h) is not possible • Contraindications for CTA: presence of pacemaker or ICD leads, AF, pregnancy, BMI >35 kg/m2, prosthetic heart valve • Previously documented myocardial infarction/PCI/CABG
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of myocardial ischemia detection using DECT in comparison to SPECT ischemia detection in patients with a intermediate to high risk of coronary artery disease, radiation dose. | — |
Primary
| Measure | Time frame |
|---|---|
| The diagnostic accuracy of the rest coronary CT angiography in combination with stress dual energy CT in comparison to SPECT and invasive coronary angiography in patients with a intermediate to high risk of coronary artery disease. | — |
Countries
Netherlands
Outcome results
None listed