gokverslaving gambling disorder obessive compulsive disorders repetitive behaviour
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion process: Potential participants are informed about the study and receive an information letter. After this, they are contacted by telephone. If interested to participate, screening for inclusion and exclusion criteria is performed, using structured diagnostic interviews, e.g. Composite International Diagnostic Interview (World Health Organisation, 1997). ;OCD group: • DSM-5 diagnosis of OCD • No other psychiatric disorder • Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score cut-off of 20 • 20-55 years of age • Willingness and ability to give written informed consent and willingness and ability to understand, to participate and to comply with the study requirements;GD group: • DSM- 5 diagnosis for Gambling Disorder • No other psychiatric disorders. • Willingness and ability to give written informed consent and willingness and ability to understand, to participate and to comply with the study requirements • 20-55 years of age;HC group: • No current psychiatric diagnosis no history of OCD or GD. • Willingness and ability to give written informed consent and willingness and ability to understand, to participate and to comply with the study requirements • 20-55 years of age
Exclusion criteria
Exclusion criteria: All groups: • Current major depressive disorder, bipolar disorder, psychotic disorder, alcohol or substance dependence, or any cognitive disorder as assessed with the MINI neurological disorders section • IQ below 80 • insufficient command of the Dutch language • MRI contraindications such as metal implants, claustrophobia, pregnancy • recent (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparing patients with compulsive disorders (GD + OCD) with heathy controls to assess pathological processes. Comparing GD patients and OCD patients to test similarities and differences in: 1) Contributions of affect and habit on compulsive behaviour with behavioral and physiological measures. 2) Confidence coding in VMPFC. 3) The effect of negative outcome anticipation on compulsive behaviour and associated brain regions. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Functional connectivity as measured with fMRI during the resting-state condition • Self-reports of development and experience of compulsions. | — |
Countries
Netherlands
Outcome results
None listed