Skip to content

The effects of pregnancy on the human brain

The effects of pregnancy on the human brain - PHB

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43856
Enrollment
160
Registered
2016-04-06
Start date
2016-06-30
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

de focus is op de effecten van een gezonde zwangerschap n.v.t.

Interventions

None listed

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Healthy women with no history of neurological disorders 2. The intention to become pregnant (experimental group) or not (control group) in the near future 3. No intracranial or intraocular metal or a pacemaker 3. Native Dutch speakers

Exclusion criteria

Exclusion criteria: 1. A history of neurological disorders 2. Intracranial or intraocular metal, pacemaker, claustrophobia

Design outcomes

Primary

MeasureTime frame
We will apply structural Magnetic Resonance Imaging, Diffusion Tensor Imaging , Magnetic Resonance Spectroscopy as well as several functional Magnetic Resonance Imaging paradigms to investigate regional tissue volumes, white matter tracts, metabolite concentrations and neural activity during rest and the performance of tasks targeting social cognition and verbal memory. In addition, the participants will perform a battery of computerized tasks, and salivary/urinary hormonal and physiological measures will be obtained.

Secondary

MeasureTime frame
n.a.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 15, 2026