Needle based CLE in thoracic lymph nodes, a comparison with pathology.

Needle based CLE in thoracic lymph nodes, a comparison with pathology. - Needle based CLE in thoracic lymhp nodes.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43854

Enrollment

Registered

2015-08-26

Start date

2016-01-13

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrathoracic lymphadenopathy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - suspected or proved NSCLC, with an indication for EUS-FNA for tissue verification of suspected mediastinal lymph nodes. - Suspected sarcoidosis stage I-II, with an indication of tissue verification of enlarged mediastinal lymph node(s) by EUS-FNA.

Exclusion criteria

Exclusion criteria: - Allergy for fluorescein - Use of Beta blocker on the day of the procedure - (Possible) pregnancy or lactation - Inability to provide informed consent - Inability to comply with study protocol

Design outcomes

Primary

Measure	Time frame
1 To describe characteristics and define interpretation criteria for nCLE imaging of: - normal/reactive lymph nodes - lymph nodes involved in lungcancer - lymph nodes involved in sarcoidosis	—

Secondary

Measure	Time frame
1. To develop an CLE image atlas for lymph nodes involved in different pulmonal diseases 2.To assess procedure-related events of needle based CLE 3. To assess technical feasibility of needle based CLE	—

Countries

Netherlands

Outcome results