A pilot study on magnetic resonance imaging of the distal radial growth plate: defining healthy and pathologic characteristics in a non-invasive manner

A pilot study on magnetic resonance imaging of the distal radial growth plate: defining healthy and pathologic characteristics in a non-invasive manner - Physeal MRI Pilot

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43849

Enrollment

Registered

2015-04-22

Start date

2015-06-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gymnast wrist radial epiphysitis

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: Symptomatic gymnast group: - Age range 12-18 years; - Open radial growth plate on hand radiograph; - Gymnastics participation in six months before inclusion, for duration a period of at least one year and up to six months or less before moment of inclusion in the study; - Wrist pain in past 6 months; - Written informed consent by participant; - Written parental consent.;Asymptomatic gymnast group: - Age range 12-18 years; - Open radial growth plate on hand radiograph; - Gymnastics participation for a period of at least one year and up to six months or less before moment of inclusion in the study; - No wrist pain in past 6 months; - Written informed consent by participant; - Written parental consent.;Non-gymnast control group: - Age range 12-18 years; - Open radial growth plate on hand radiograph; - No gymnastic participation at present or in the past; - No participation of other wrist-loading sport with risk of wrist overuse injury (i.e. racquet sports, volleyball, field hockey, rowing, judo) for more than twice a week; - No history of wrist trauma, such as wrist fracture; - Written informed consent by participant; - Written parental consent.

Exclusion criteria

Exclusion criteria: - History of past fracture, infection or surgery of the wrist; - Diagnosed with any growth disorder; - Diagnosed with systemic disease involving the musculoskeletal system (e.g. juvenile idiopathic arthritis); - Oncological disease involving the musculoskeletal system; - Fully closed growth plate on wrist radiographs, indicative of skeletal maturation; - No written informed consent.

Design outcomes

Primary

Measure	Time frame
Early signs of growth plate injury on conventional radiographs, standard MRI sequences and on MRI sequences sensitive for cartilage imaging, such as oedema, bony bridges and growth plate widening;	—

Secondary

Measure	Time frame
- Skeletal age as determined from a hand radiograph; - Signs of distal radial growth plate injury on hand radiographs, such as widening and haziness of the growth plate; - Quantification of growth plate pathology on DWI MR images using ADC maps; - Growth plate volume derived from 3D mapping; - Growth plate thickness; - Clinical signs and severity of distal radial growth plate injury such as wrist pain; - Anthropomorphic characteristics (length, weight) and training characteristics (starting age, level, training intensity in hours, training frequency in days, specialty elements) of participants.	—

Measure

Time frame

- Skeletal age as determined from a hand radiograph; - Signs of distal radial growth plate injury on hand radiographs, such as widening and haziness of the growth plate; - Quantification of growth plate pathology on DWI MR images using ADC maps; - Growth plate volume derived from 3D mapping; - Growth plate thickness; - Clinical signs and severity of distal radial growth plate injury such as wrist pain; - Anthropomorphic characteristics (length, weight) and training characteristics (starting age, level, training intensity in hours, training frequency in days, specialty elements) of participants.

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Countries

Netherlands

Outcome results