Identification of novel childhood osteosarcoma predisposing genes.

Identification of novel childhood osteosarcoma predisposing genes. - Osteosarcoma predisposition

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43835

Enrollment

Registered

2017-06-22

Start date

2017-09-25

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone cancer osteosarcoma

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: 20 individulas who have developed osteosarcoma in childhood (

Exclusion criteria

Exclusion criteria: - A proven osteosarcoma predisposing condition - A genetic defect in the family for a cancer unrelated condition, of which the child might be a carrier but about which the child/parents do not want to be informed.

Design outcomes

Primary

Measure	Time frame
Understanding the molecular etiology and pathogenesis of CRC in AYAs is expected to yield novel genetic risk factors. that will facilitate clinical decision making, including early tumor detection, in AYAs with CRC and their siblings at risk.	—

Secondary

Measure	Time frame
Identification of novel genetic risk factors voor CRC will facilitate clinical decision making, including early tumor detection in AYAs with CRC and their siblings at risk.	—

Countries

Netherlands

Outcome results