cerebrovascular accident (CVA stroke)
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: General: 18 years or older, male/female, have command of the Dutch language. Additional for stroke: survivor of a cerebrovascular accident (stroke) Additional for PD: Diagnosed with PD according to the UK PD Brain Bank criteria Additional for patients with tremor: tremor of the hand and/or arm, having a scheduled visit for tremor assessment at the Clinical Neurophysiology outpatient clinic at LUMC. Additional for healthy controls: normal function of both arms, normal gait and balance function, normal cognitive function (MoCA score > 26), normal or corrected to normal vision
Exclusion criteria
Exclusion criteria: General: * additional neurological diseases and/or orthopedic problems interfering with hand/arm function or balance/gait function * unable to comply with the protocol, i.e. insufficient general fitness or cognitive/communicative inability to understand instructions and participate in the measurement * inability to walk with help of one person (for the *gait and balance* experiment only);Additional for stroke: *
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kinematic parameters obtained for reaching and grasping (e.g., maximum active range of motion, accuracy, velocity and smoothness of reach and grasp movements), for gait and balance (e.g., step length, step time, gait asymmetry, performance on an obstacle avoidance task), and for tremor (frequency, amplitude) as a function of task- and environmental conditions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical test scores For stroke patients in general: Montreal Cognitive Assessment, Letter Cancellation Test, Beck Depression Index and Nottingham Extended Activities of Daily Living; Additional for stroke patients participating in the *reaching and grasping* experiment: Fugl-Meyer - Upper Extremity, Action Research Arm Test, Ashworth score of the elbow and wrist, Erasmus modification of the Nottingham Sensory Assessment - Upper Extremity and Michigan Hand Outcome Questionnaire; Additional for stroke patients participating in the "gait and balance" experiment: Timed Up-and-Go, 10 m walk test, Functional Reach test, Tinetti Balance Assessment, short version of the Berg Balance Scale, Falls Efficacy Scale * International, Ashworth score of the knee and ankle, and the Modified Survey of Activities and Fear of Falling in the Elderly Scale For PD patients in general: Movement Disorder Society version of the Unified Parkinson Disease Rating Scale [MDS-UPDRS], the Scales for Outcomes in Parkinson*s Disease - Cognition [SCOPA-COG] and Psychiatric Complications [SCOPA-PC], Beck Depression Index and Questionnaire for Impulsive-Compulsive Disorders in Parkinson*s Disease * Rating Scale [QUIP-RS]; Additional for PD patients participating in the *reaching and grasping* experiment: Michigan Hand Outcome Questionnaire; Additional for PD patients participating in the "gait and balance" experiment: Timed Up-and-Go, 10 m walk test, Functional Reach test, Tinetti Balance Assessment, short version of the Berg Balance Scale, Falls Efficacy Scale * International, the New Freezing of Gait questionnaire, the Modified Survey of Activities and Fear of Falling in the Elderly Scale, and the SEverity of Non-dopaminergic Symptoms in Parkinson*s Disease scale. For patients with tremor: Bain and Findley Clinical tremor rating scale, Bain and Findley tremor ADL scale Other: age, sex, education level, work, dominant side, (most) affected side, disease duration, curre | — |
Countries
Netherlands
Outcome results
None listed