Multi-Site RCT of Group Schema Therapy for Borderline Personality Disorder

*Multi-Site RCT of Group Schema Therapy for Borderline Personality Disorder* - 'Group Schema Therapy for BPD'

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON43782

Enrollment

321

Registered

2010-01-13

Start date

2010-01-15

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline Personality Disorder personality problems

Interventions

1. Group Schema Therapy A (Group-focused): 124 group sessions plus 0-18 individual sessions 2. Group Schema Therapy B (Group and individual combined): 74 group sessions plus 62 individual sessions

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 year 2. Primary DSM-IV diagnosis of BPD (assessed with the SCID-II interview) 3. BPD severity above 20 on the BPDSI interview 4. Willingness to participate in the study (informed consent procedure) 5. Ability to participate in (group) treatment and research for 2 years (e.g., no plans to move to other city)

Exclusion criteria

Exclusion criteria: 1. Lifetime psychotic disorder (short stress-related episodes are allowed, as described in DSM-IV BPD criterion 9) 2. IQ

Design outcomes

Primary

Measure	Time frame
The primary outcome is reduction in BPD-severity assessed by the BPDSI interview (Arntz et al., 2003; Giesen-Bloo et al., 2006). Use of the BPDSI will allow direct comparisons with the other studies of ST: Giesen-Bloo et al. (2006), van Asselt et al. (2008), and Nadort et al. (2008, 2009).	—

Secondary

Measure	Time frame
Secondary outcomes include the dimensional subscales and total score of the BPDSI. Furthermore, the following self-report instruments will be used: the BPD-checklist (self report of burden of BPD manifestations); the SCL-90; the Young Schema Questionnaire; the Schema Mode Inventory (Lobbestael et al., 2008). Quality of Life will be assessed with the WHOQOL (short version; The WHOQOL Group, 1998), the EuroQol (Brooks 1996; Dolan, 1997), and the one-item happiness question, of which norms are available of 33 countries, including the US, Germany, the Netherlands and Norway,)(Veenhoven, 2008). General functioning will be assessed with the GAF (DSM-IV), and social and occupational functioning with the Social and Occupational Functioning Assessment Scale (SOFAS; DSM-IV; Goldman et al., 1992). Both are assessed by independent raters blind for condition, using a semi-structured interview (Bamelis et al., in progress). Social functioning will be also assessed with a self-report form, the Work and Social Adjustment Scale (WSAS) (Marks et al., 1973; Mataix-Cols et al., 2005) and the SAS-SR (Weissman & Bothwell, 1976) to allow comparability to other studies conducted in the USA.	—

Measure

Time frame

Secondary outcomes include the dimensional subscales and total score of the BPDSI. Furthermore, the following self-report instruments will be used: the BPD-checklist (self report of burden of BPD manifestations); the SCL-90; the Young Schema Questionnaire; the Schema Mode Inventory (Lobbestael et al., 2008). Quality of Life will be assessed with the WHOQOL (short version; The WHOQOL Group, 1998), the EuroQol (Brooks 1996; Dolan, 1997), and the one-item happiness question, of which norms are available of 33 countries, including the US, Germany, the Netherlands and Norway,)(Veenhoven, 2008). General functioning will be assessed with the GAF (DSM-IV), and social and occupational functioning with the Social and Occupational Functioning Assessment Scale (SOFAS; DSM-IV; Goldman et al., 1992). Both are assessed by independent raters blind for condition, using a semi-structured interview (Bamelis et al., in progress). Social functioning will be also assessed with a self-report form, the Work and Social Adjustment Scale (WSAS) (Marks et al., 1973; Mataix-Cols et al., 2005) and the SAS-SR (Weissman & Bothwell, 1976) to allow comparability to other studies conducted in the USA.

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)

*Multi-Site RCT of Group Schema Therapy for Borderline Personality Disorder*