Feeding behavior Response to feeding
Conditions
Interventions
Four different *milkshakes* of 165ml with added sugars and sweeteners.
Sponsors
Unilever
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Signed informed constent Age between 18 and 25 years Bodyweight of at least 70 kg BMI between 20 and 23 kg/m2
Exclusion criteria
Exclusion criteria: -Diabetes or history of other disturbances of glucose metabolism (eg impaired glucose tolerance, hypoglycemia). -Any genetic or psychiatric disease (e.g. fragile X syndrome, major depression) affecting brain -Any significant chronic disease -Any known food allergies or intolerances -Renal or hepatic disease -Recent weight changes or attempts to lose weight (> 3 kg weight gain or loss, within the last 3 months) -Smoking (current or last 6 months) -Alcohol consumption of more than 21 units per week or use of recreational drugs at present or in the last year -Recent participation in other biomedical research projects (within the last 3 months), participation in 3 or more biomedical research projects in one year -Contra-indication to MRI scanning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in brain connectivity and activity, as measured by rsfMRI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Psychophysical ratings of hunger, taste and sweetness | — |
Countries
Netherlands
Outcome results
None listed