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Using TMS-EEG to assess effective connectivity

Using TMS-EEG to assess effective connectivity - TMS-EEG and connectivity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON43761
Enrollment
96
Registered
2015-06-30
Start date
2016-05-25
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuroscientific research N/A

Interventions

Participants will receive TMS pulses, the effects of which will be measured using EEG. The number, frequency, and intensity of the TMS pulses will be within published safety norms (Rosse et al., 200

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Only healthy, competent, participants, 18*45 years old, with normal vision or corrected-to normal vision by means of contact lenses.

Exclusion criteria

Exclusion criteria: - Serious head trauma or brain surgery - Previous history of epilepsy - Large or ferromagnetic metal parts in the head (except for a dental wire) - Implanted cardiac pacemaker or neurostimulator - Pregnancy - Large of ferromagnetic metal parts in the body - Claustrophobia - Skin diseases at intended electrode sites - Disorders of vision (i.e., deviation from *normal or corrected-to-normal vision*) - History or current presence of any neurologic or psychiatric disease - Any prescribed medication that can alter cortical excitability (e.g. antiepileptics, tricyclic anti-depressives or benzodiazepines) or can have an influence on the participant*s vigilance or cognitive performance within two weeks prior to participation.

Design outcomes

Primary

MeasureTime frame
The amplitude of the TMS-evoked potential (TEP) in the EEG as a function of (1) stimulation area, (2) the presence or absence of an earlier pulse over connected brain areas, and (3) cognitive condition.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)