geen n.a.
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy, younger and older Caucasian adults, males and females; Between18-30 and 60-75 year old; Right-handed; Normal (or corrected to normal) vision; Normal BMI (18-25 kg/m2); fMRI compatible.
Exclusion criteria
Exclusion criteria: Not matching any of the inclusion criteria, as well matching any criterion in the fMRI exclusion list, including, but not limited to, claustrophobia, infarctions, epilepsy or family history of epilepsy, presence of metal inside the body, presence of electric/electronic devices inside the body (pacemakers, etc.), presence of intracardial lines, users of non-removable dentures. Psychoactive medication, including antidepressants, anxiolytic, and anti-epileptic drugs, as well as cannabis, XTC or other recreational drugs, (suspected) Pregnancy, intra-utrine device with metal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are: the choices participants make on each trial, the switching behaviour of the participants (sequential choices) and the brain activity corresponding to those. The outcome of the study (endpoints) will consist of: the neural mechanisms associated stimulus-reward association updating; a description of the age-related differences in those mechanisms. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands