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Variability of quantitative Ga68-PSMA PET: a test-retest pilot study

Variability of quantitative Ga68-PSMA PET: a test-retest pilot study - Ga68-PSMA test-retest study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43731
Enrollment
30
Registered
2017-03-22
Start date
2018-01-24
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer with biochemical relapse recurrent prostate cancer

Interventions

None listed

Sponsors

Catharina-ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Biochemical recurrence of prostate cancer and eligible for PSMA PET for restaging and at least one visually PSMA positive tumour site and mentally competent

Exclusion criteria

Exclusion criteria: Age

Design outcomes

Primary

MeasureTime frame
Quantification of absolute PSMA uptake (SUVmax en SUVpeak) and intrapatient variability of PSMA uptake in tumor lesions and normal tissues, including muscles, liver, spleen, bone marrow. Primary endpoints: Absolute values and intrapatient variability of PSMA uptake in tumor lesions Absolute values and intrapatient variability of PSMA uptake in muscle Absolute values and intrapatient variability of PSMA uptake in liver Absolute values and intrapatient variability of PSMA uptake in spleen Absolute values and intrapatient variability of PSMA uptake in bone marrow Absolute values and total variability of PSMA uptake in all tumor lesions irrespective of size

Secondary

MeasureTime frame
Quantification of absolute values and intrapatient variability in PSMA uptake in tumour lesions and normal tissue, with or without Q.Clear reconstruction. Secondary endpoints: 2.2.1 Secundaire eindpunten: Absolute values and intrapatient variability of PSMA uptake in small tumor lesions = 3 cc, with or without Q.Clear Absolute values and intrapatient variability of PSMA uptake in muscle, with or without Q.Clear Absolute values and intrapatient variability of PSMA uptake in liver, with or without Q.Clear Absolute values and intrapatient variability of PSMA uptake in spleen, with or without Q.Clear Absolute values and intrapatient variability of PSMA uptake in bone marrow, with or without Q.Clear

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)