osteoarthritis
Conditions
Interventions
Training protocol for gait modification once every week during 6 weeks,
including feedback on the external knee adduction moment (KAM) and advice on
home training.
feedback
gait
knee
osteoarthritis
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the present study (A and B) are knee osteoarthritis on the medial compartment based on the ACR criteria, age between 50 and 75 years old, Body Mass Index (BMI) between 20 and 30 kg/m2, maximum score of 7 on the numeric rate scale (NRS) for pain intensity during the past two weeks. Additional inclusion criteria for study B is satisfaction with applied gait modification pattern in study A, willingness to further learn this pattern and clear improvement in knee adduction moment (approximately 10% reduction). This will be at the discretion of the physiotherapist involved who will have the final decision on inclusion.
Exclusion criteria
Exclusion criteria: Total knee replacement, rheumatoid arthritis or any other form of inflammatory arthritis (i.e., crystal arthropathy or septic arthritis). Similarly patients with hip osteoarthritis will be excluded, as will people with poor vision that would prevent them from being able to see the visual feedback. Patients who are already included in any other experimental research study (including but not limited to the Vitamin D study and the COOA study) will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures are change in external knee adduction moment (KAM) between different conditions. KAM will be measured during the various gait modification conditions (study A: 1. baseline; 2. KAM feedback without kinematic instructions, audio and visual feedback; 3. Kinematic feedback without further instructions (toe-out or -in, step width and medial thrust); 4. KAM feedback with additional verbal kinematic instructions about an effective gait pattern that can be sustained in daily life: 5. maintaining the pattern from 4. without any feedback) and during and after the training sessions (study B: 1. baseline; 2. try to replicate the pattern learned in study A without feedback; 3. KAM feedback with kinematic instructions from study A; 4. maintaining the pattern from 3. without feedback; follow-up after 3 and 6 months). Linear mixed models will be used to calculate statistical differences. Pain as measured by the numeric rating scale and WOMAC questionnaire will also be a primary outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters will include external knee flexion moment (KFM), and kinematic pattern (joint angles and temporal-spatial parameters) as measured by the GRAIL; these will be assessed during the different gait modification patterns (as for the KAM). EMG cocontraction is also a secondary outcome. | — |
Countries
The Netherlands
Outcome results
None listed