Infecties, verergering onderliggend medisch lijden exacerbation of age-related diseases during travel
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - 60 years and older; - Planned travel to the (sub)tropics. (Sub)tropical areas are defined as countries where hepatitis A is endemic and for which vaccination is recommended according to the LCR. -Travel duration of five weeks (35 days) or less. - Ability to complete the questionnaires and diary. - Ability to speak and read Dutch fluently. - Ability to sign the informed consent form.
Exclusion criteria
Exclusion criteria: - 59 years or younger. - Travel to a destination for which no hepatitis A vaccination is recommended according to the LCR. - Inability to complete questionnaires and diary. - Travel duration longer than 5 weeks (>35 days) - Visit to travel clinic is less than two weeks before departure. - Inability to speak or read Dutch. - Inability to complete questionnaire and diary. - Incapacitated travelers. - Absence of written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main endpoints of the primary objective are the occurrence, duration in days and morbidity of an acquired illness during travel and four weeks after return. The focus will be on different type of health complaints: - Fever - Gastrointestinal - Respiratory - Dermatological - Cardiovascular - Genitourinary tract Other endpoints of the objective are: - Hand grip strength in kilograms before travel (vitality). - Patient-reported health before, during and after travel (SF-36 and Charlson Comorbidity Index). - Independence in activities of daily living (Katz-ADL). - Cognitive functioning before travel (6CIT). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Frequency of medical conditions before travel (e.g. diabetes mellitus, COPD, cardiovascular disease) - Frequency of medication use before travel - Number of medicines used before travel (e.g. polypharmacy) - Frequency of infectious or non-infectious illnesses during travel or in the Netherlands until four weeks after return - Frequency of a new medical condition or an exacerbation of underlying medical condition during travel or in the Netherlands until four weeks after return - Percentage of medication adjustments during travel and four weeks or in the Netherlands until four weeks after return - Frequency of self-reported compliance with prescribed antimalarials during travel - Frequency of doctor visits abroad or in the Netherlands until four weeks after return - Frequency and duration of hospitalizations abroad or in the Netherlands until four weeks after return Other study parameters Demographical parameters - Gender - Age - Education level - Weight (in kilograms) - Length (in centimetres) - Body Mass Index (BMI), weight/(length in meter2) - Immigrant Travel parameters - Destination - Duration - Type of travel - Type of accommodation - Self-reported risk behaviour during travel (nutrition, hygiene, activities) - Jetlag - Travel health insurance, covering medical costs and repatriation. | — |
Countries
Netherlands
Outcome results
None listed