Asynchrony of spontaneous breathing and respiratory support diaphragm activity
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: - Born at less than 32 weeks of gestational age - Receiving nIPPV to treat apnea of prematurity - Written parental informed consent
Exclusion criteria
Exclusion criteria: - Major congenital anomalies - Clinical instability requiring frequent interventions by the nursing staff, that may interfere with the measurement -The attending physician considers the infant to be too vulnerable to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of synchronicity of ventilator flow cycles and spontaneous breaths of the infant detected by transcutaneous electromyography of the diaphragm (dEMG). Asynchrony index: defined as asynchronous (not- or insufficiently synchronous) breaths divided by all breaths. | — |
Secondary
| Measure | Time frame |
|---|---|
| dEMG amplitude variations and volume changes measured with respiratory inductance plethysmography between synchronous and asynchronous breaths. | — |
Countries
Netherlands
Outcome results
None listed