The effects of short-term exercise and protein supplementation on muscle strength, muscle mass and physical fitness in untrained older adults

The effects of short-term exercise and protein supplementation on muscle strength, muscle mass and physical fitness in untrained older adults - STEP: Short Term Exercise and Protein

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON43655

Enrollment

Registered

2016-02-18

Start date

2016-03-29

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

n.v.t. dit onderzoek betreft géén aandoening. not applicable

Interventions

The intervention period is 4 weeks. The intervention consists of an exercise component and protein supplementation. Exercise program: a. Supervised: twice a week a supervised exercise sessions of a

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Aged 55 to 75 years • Not meeting the Dutch Norm for Health-enhancing Physical Activity; the subject is not involved in >= 30 min of at least moderate-intensity aerobic physical activity on >= 5 days per week (assessed with physical activity questionnaire) • No participation in any structured or regular exercise training programs for the last 3 months.

Exclusion criteria

Exclusion criteria: • Allergic or sensitive for milk proteins, or lactose intolerant • Diagnosed with renal insufficiency • On a diet which affects protein intake (i.e. advices of an increase, decrease or type of protein (intake)) • Having known contraindications for exercise • Diagnosed with cancer for which currently treated • Having a contraindication to MRI scanning (including, but not limited to): * pacemakers and defibrillators * intraorbital or intraocular metallic fragments * ferromagnetic implants * claustrophobia • Participation in other intervention trial • Unable to understand Dutch • Having no general physician.

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study is the change in isometric quadriceps strength (Biodex). Quadriceps strength is measured at baseline, after 2 and after 4 weeks.	—

Secondary

Measure	Time frame
Secondary parameters are changes quadriceps cross sectional area and volume (MRI and ultrasound), handgrip strength (dynamometer), power of the lower limb (chair rise time test), physical fitness (Åstrand-Rhyming test), habitual physical activity (accelerometer) and daily protein intake (24h recall questionnaire). Parameters are assessed at baseline, 2 weeks and 4 weeks. Habitual physical activity and protein intake will be assessed at baseline and after 4 weeks.	—

Measure

Time frame

Secondary parameters are changes quadriceps cross sectional area and volume (MRI and ultrasound), handgrip strength (dynamometer), power of the lower limb (chair rise time test), physical fitness (Åstrand-Rhyming test), habitual physical activity (accelerometer) and daily protein intake (24h recall questionnaire). Parameters are assessed at baseline, 2 weeks and 4 weeks. Habitual physical activity and protein intake will be assessed at baseline and after 4 weeks.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)