Tidal ventilation distribution and patient-ventilator synchrony during Proportional Assist Ventilation with load-adjustable gain factors

Tidal ventilation distribution and patient-ventilator synchrony during Proportional Assist Ventilation with load-adjustable gain factors - Ventilation distribution during PAV+

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON43588

Enrollment

Registered

2016-11-10

Start date

2017-11-20

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory distress respiratory insufficiency

Interventions

Subjects are ventilated for 2-3 days with either NAVA (Group I) or PAV+ (Group II). Thereafter, the subject is ventilated using three levels of NAVA and three levels of PAV+ for 10 minutes each whil

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Subject received mechanical ventilation with the Pressure Support mode and/or Neurally Adjusted Ventilatory Assist mode for at least 16 hours.

Exclusion criteria

Exclusion criteria: Hemodynamic instability, respiratory distress during mechanical ventilation at inclusion, lack of spontaneous breathing effort.

Design outcomes

Primary

Measure	Time frame
The main study endpoints are a shift of tidal impedance variation from the ventral and central area of the lung towards central and dorsal area of the lung, and stable PAV+ ventilation for 2-3 days.	—

Secondary

Measure	Time frame
The secondary objective is to assess the applicability of PAV+ in our current ICU population.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)