hemiparesis impaired arm-hand function due to a stroke
Conditions
Interventions
None listed
Sponsors
Adelante
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Stroke patients: • Chronic unilateral supratentorial stroke; • Post-stroke time > 12 months; • Age >= 18 years; • Severely impaired arm-hand function (AHF): Utrechtse Arm-hand Test (UAT) score 0-1; • Ability to comprehend the test and measurement instructions (in Dutch).;Healthy persons: - age >=18 years - no history of stroke - no impaired arm-hand function - able to comprehend the test and measurement instructions in Dutch.
Exclusion criteria
Exclusion criteria: CVA patienten: • Severe cognitive impairments; • Spasticity in the affected arm-hand: Modified Ashworth Scale (MAS) score >=2; • Severe additional orthopaedic, rheumatoid, neurologic impairments of the body that may *further impede arm-hand task execution; • No informed consent. ;• MRI contra-indications: epilepsy, claustrophobia, medication, metal parts in the body (metal plates or screws, clips on blood vessels, braces, metal wire behind teeth, prostheses, piercings, tattoos (including permanent makeup), artificial cardiac valve, anticonception spiral, metal splinters, pacemaker, insulin pump, other electronic devices)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a) Motor performance level (FM, ARAT, ABILHAND); b) Hand motor performance and brain activation patterns during task performance (fMRI); c) Reaction time / movement time (button-press task); d) Grip force e) Somatosensory hand performance (fMRI); f) T1-weighted anatomical scans and resting state scans (fMRI). | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed