endometrium cancer Endometrium carcinoma
Conditions
Interventions
None listed
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Patients scheduled for elective laparoscopic hysterectomy, laparoscopic staging procedures, laparoscopic radical hysterectomy. * Adult patients (older than 18 years of age) * Written informed consent * Understanding of Dutch or English language
Exclusion criteria
Exclusion criteria: * Non-elective surgery * Any contraindication to neuraxial blockade (including coagulopathy, abnormal anatomy) * Allergy to amide-linked local anaesthetics, especially bupivacaine * Known psychiatric disorder * Chronic pain patients or patients already using morphine pre-operatively
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of cytokines (pro- and anti-inflammatory), procalcitonin, NLR and C-reactive protein | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Intensity of wound pain at rest and during movement by Numeric Rating Scale 2) The number of milligrams of opioids and NSAID consumed by the patient. 3) Health-related quality of life (HR-QOL) will be determined by EuroQol instrument (EQ-5D). 4) Side effects such arrhythmias, hemodynamic changes and post epidural headache will be registered and recorded as absent or present. 5) Length of hospital stay will be calculated and expressed in number of days. | — |
Countries
Netherlands
Outcome results
None listed