FindTrial
Sign In

Neural mechanism of anticipatory postural control during rapid voluntary arm movement in young and elderly people.

Neural mechanism of anticipatory postural control during rapid voluntary arm movement in young and elderly people. - Neural mechanism in elderly people

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43443
Enrollment
86
Registered
2016-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Veroudering Aging

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age 18 and older, male and female gender.

Exclusion criteria

Exclusion criteria: Neurological disorders like epileptic, MS, dementia, inability to stand independently for 10 minutes without rest, medications know to affect balance, any metal in the brain/skull, pregnancy or suspicion of pregnancy (self-reported).

Design outcomes

Primary

MeasureTime frame
The main study parameters are the size of a reflex, called H reflex, measured in response to peripheral electrical stimulation if the tibial nerve and normalized for the maximal compound action potential or M wave. That is, the H/M ratio. A second outcome is short-interval intracortical inhibition or SICI, which is the inhibition of the test motor evoked potential (MEP), when the suprathreshold TMS pulse (the test stimulus) is preceded by a few milliseconds with a subthreshold TMS pulse (the conditioning stimulus). SICI is a measure of motor intracortical inhibition, reflecting GABAergic receptors function.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)