ADHD attention deficit disorder
Conditions
Interventions
Volunteers will be treated with the dietary supplement tyrosine or a placebo on
three testing days. They will either receive 0, 50 mg/kg body weight, or 100
mg/kg tyrosine.
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Between 18 and 35 years of age; Willingness to sign an informed consent; Showing ADHD symptoms, but not sufficient for the diagnosis; BMI of 18.5-30.
Exclusion criteria
Exclusion criteria: Use of recreational drugs in the past month; Excessive drinking; Pregnancy; Use of ADHD medication in the past; Allergy for tyrosine containing substances;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the number of Commission errors derived from the continuous performance test (CPT). | — |
Secondary
| Measure | Time frame |
|---|---|
| The following secondary parameters will be tested in this study: * performance on the stop-signal task as a measure of motor inhibition; * performance on the verbal learning task as a measure for working memory and long-term memory; * the task-switching task as a measure to assess switching attention; * the Profile of Mood States and Bond & Lader as measures of mood and perceived alertness; * blood biomarkers, from which the amount of tyrosine and prolactine will be analysed, as measure of the association between amount of uptake and cognitive performance. | — |
Countries
Netherlands
Outcome results
None listed